Selected publications Lars Alfredsson
Klareskog L, Stolt P, Lundberg K, Källberg H, Silva C, Grunewald J, Rönnelid J, Erlandsson Harris H, Ulfgren AK, Rantapää-Dahlqvist S, Eklund A, Padyukov L, Alfredsson L. A new model for an etiology of RA; Smoking may triffer HLA-DR (SE)- resticted immune reactions to autoantigens modified by citrullination. Arthritis Rheum 2006;54(1):38-46.
Kallberg H, Padyukov L, Plenge RM, Ronnelid J, Gergersen PK, van der Helm-van Mil AMH, Toes REM, Huizinga TW, Klareskog L, Alfredsson L. Gene-gene and gene-environment interactions involving HLA-DR, PTPN22 and smoking in two subsets of rheumatoid arthritis. Am J Hum Genet. 2007 May;80(5):867-75.
Plenge RM, Seielstad M, Padyukov L, Lee AT, Remmers EF, Ding B, Liew A, Khalili H, Chandrasekaran A, Davies LR, Li W, Tan AK, Bonnard C, Ong RT, Thalamuthu A, Pettersson S, Liu C, Tian C, Chen WV, Carulli JP, Beckman EM, Altshuler D, Alfredsson L, Criswell LA, Amos CI, Seldin MF, Kastner DL, Klareskog L, Gregersen PK. TRAF1-C5 as a Risk Locus for Rheumatoid Arthritis -- A Genomewide Study. N Engl J Med. 2007 Sep 20;357(12):1199-209. Epub 2007 Sep 5.
Mahdi H, Fisher B, Källberg H, Plant D, Malmström V, Rönnelid J, Charles P, Ding B, Alfredsson L, Padyukov L. Symmons DPM, Venables PJ, Klareskog L, Lundberg K. Specific interaction between genotype, smoking and autoimmunity to citrullinated alfa-enolase in the etiology of rheumatoid arthritis. Nature Genetics. 2009 Dec;41(12):1319-24.
Saevarsdottir S, Wedrén S, Seddighzadeh M, Bengtsson B, Wesley AM, Lindblad S, Askling J, Alfredsson L, Klareskog L. Patients with early rheumatoid arthritis who smoke are less likely to respond to treatment with methotrexate and TNF inhibitors. Observations from the EIRA cohort and the Swedish Rheumatology Register. Arthritis Rheum. 2011 Jan;63(1):26-36. doi: 10.1002/art.27758.
« Back